Week 1 vs. Rams (Sept. 8)
4-1 - Carolina's record against the reigning NFC champions since 2015 in meetings with Philadelphia, Atlanta and Seattle. The Panthers have played the NFC champion every season since 2008.
Week 2 vs. Buccaneers (Sept. 12, Thursday Night Football)
110.4 - Cam Newton's passer rating in six games against Tampa Bay at home. Newton went 5-1 in those contests, averaging 231 passing yards and nearly two passing touchdowns per game.
Week 3 at Cardinals (Sept. 22)
422 - Passing yards by Newton in his first career game at Arizona in Week 1 of 2011. It marked the most passing yards by any NFL quarterback in his rookie debut.
Week 4 at Texans (Sept. 29)
4 - Number of total games Carolina has played against Houston, the fewest matchups between the Panthers and any other current NFL team. The all-time series is 2-2.
Week 5 vs. Jaguars (Oct. 6)
22 - Margin of total wins Carolina has over Jacksonville since both teams entered the NFL in 1995. Both franchises are celebrating 25 seasons in 2019 with Carolina holding a 199-201 all-time record and Jacksonville standing at 177-221.
Week 6 at Buccaneers in London (Oct. 13)
6,419 - Kilometers from Charlotte to Tottenham Hotspur Stadium in London, home of Carolina's first international game and the farthest road game in franchise history.
Week 8 at 49ers (Oct. 27)
70.0 - Carolina's win percentage (7-3) in road games against San Francisco (both teams were in the NFC West back in the day). Since 1995, only Dallas (5-1) and Green Bay (4-1) have a better winning percentage at the 49ers.
Week 9 vs. Titans (Nov. 3)
0 - Number of home wins that Carolina has against the Tennessee Titans. The Titans are the only team that Carolina has never beaten in Charlotte, going 0-2 at home. That can change in Week 9.
Week 10 at Packers (Nov. 10)
3 - Degrees Fahrenheit in Carolina's coldest game in franchise history, the NFC Championship contest at Lambeau Field on Jan. 12, 1997. This year's game in Week 10 is Carolina's last road game outdoors with three games at Atlanta, New Orleans and Indianapolis following in November and December.
Week 11 vs. Falcons (Nov. 17)
26 - Total receptions by Christian McCaffrey in two games against the Falcons in 2018. He tied Steve Smith's single-game franchise record with 14 catches at Atlanta in Week 2 and then posted 12 catches at home against Atlanta in Week 16. It marked the most receptions by a running back against an opponent in one regular season in NFL history.
Week 12 at Saints (Nov. 24)
12 - Total point differential in the all-time series against New Orleans, which Carolina leads 1,082 -1,070. The Panthers have a 25-24 edge in the all-time series against Carolina's most common opponent.
Week 13 vs. Redskins (Dec. 1)
6 - Wins in eight games by Carolina over the Redskins since divisional realignment in 2002. The Redskins started the all-time series with six consecutive victories between 1995 and 2001, so they're clinging to an 8-6 edge overall.
Week 14 at Falcons (Dec. 8)
7 - Players that attended high schools in the state of Georgia on the current Panthers roster.
Week 15 vs. Seahawks (Dec. 15)
10 - This year marks the 10th meeting between Seattle and Carolina since 2010, including the playoffs. It marks the most games against any team outside of the division in that stretch.
Week 16 at Colts (Dec. 22)
3:50 - The length of time of Carolina's third-longest game in franchise history – a home overtime win on Monday Night Football in the last meeting with the Colts in 2015. Two of Carolina's five all-time wins over Indianapolis have come in overtime.
Week 17 vs. Saints (12/29)
10th - Time that Carolina has closed the regular season with a game against the New Orleans Saints in franchise history. The Saints are Carolina's most common year-ending opponent.
Additionally, Carolina has only finished the regular season at home once in the Ron Rivera/Cam Newton era, and that was in...2015.
Scroll through pictures of Carolina playing its 2019 opponents.
Carolina faces off against the Rams in the season opener. It marks the second consecutive season that the Panthers have started at home and the second time ever playing the Rams in a season opener.
The Panthers play the Buccaneers on Thursday Night Football at home in Week 2. It marks the fifth time since 2006 that the Panthers and Bucs have played in primetime.
Carolina hasn't played at Arizona since 2013. In 2011, Cam Newton set an NFL record with 422 passing yards in his rookie debut at Arizona.
Richie Brockel scored a touchdown on a trick play in Carolina's last trip to Houston in 2011. The Panthers have only played the Texans four times in franchise history, the fewest of any team.
The Panthers last played the Jaguars at home in the infamous rain game of 2011. That also marked the first victory of head coach Ron Rivera and quarterback Cam Newton's tenure.
Carolina plays the Buccaneers in London in the Panthers' first international game in franchise history.
Carolina plays at San Francisco in Week 8 after the bye. The Panthers have won the game after the bye week in four straight seasons.
The Panthers have only played the Titans twice at home in franchise history. Tennessee is the last team that Carolina has yet to beat at home, but they will get their chance in Week 9.
Carolina is 2-4 all-time at Lambeau Field with wins coming in 2008 and 1999.
Carolina is 4-3 at home against the Falcons since 2012.
There is only a 12-point total differential in the all-time series against New Orleans, which Carolina leads 1,082 -1,070. The Panthers have a 25-24 edge in the all-time series against Carolina's most common opponent.
The Panthers have won the last four home games against the Redskins, including a 44-16 victory in 2015.
In 2018, Christian McCaffrey had 26 total receptions in two games against the Falcons. He tied Steve Smith's single-game franchise record with 14 catches at Atlanta in Week 2 and then posted 12 catches at home against Atlanta in Week 16. It marked the most receptions by a running back against an opponent in one regular season in NFL history.
This year marks the 10th meeting between the Panthers and Seahawks since 2010, including the playoffs. It marks the most games against any team outside of the NFC South in that span.
Carolina is 3-0 all-time at Indianapolis, including a 27-19 win in the last matchup in Indy in 2011.
Week 17 marks the 10th time in franchise history that Carolina has closed the season against the Saints. Carolina has met New Orleans in more season finales than any other opponent.
