After starting the season 0-1, the Panthers will look to even their record on the road against the Buccaneers. Here are five things to watch for in the matchup.
Will the Bucs contain McCaffrey again?
Tampa Bay was the league's No. 1 rush defense last year, allowing just 3.7 yards per carry and 1,181 total yards on the ground. They were the one team to truly contain running back Christian McCaffrey, as he had just 53 yards from scrimmage in the first meeting and 57 yards in the second.
While the Buccaneers lost to the Saints last week, they allowed only 2.4 yards per carry, picking up right where they left off under defensive coordinator Todd Bowles.
"They've got big, powerful guys inside," head coach Matt Rhule said. "They're going to load the box. They're going to bring pressure. They want you to play under duress."
The Panthers offense runs through McCaffrey, and coordinator Joe Brady's task is to find creative ways to get him the ball. But the offense has other weapons, like wide receivers Robby Anderson, Curtis Samuel, and DJ Moore. As Rhule put it, the club wants to be well rounded enough that if one option gets taken away, they can turn to another and still find success.
Can the Panthers generate a pass rush?
Carolina didn't do much to pressure Las Vegas quarterback Derek Carr last week, recording zero sacks and zero quarterback hits. If that continues this week, it's fair to assume Bucs quarterback Tom Brady will carve up the Panthers' defense.
Rhule said this week: The best way to get after Brady is to generate pressure with four down linemen, leaving the rest of the defense in coverage. Kawann Short's absence due to a foot injury will make that harder. Zach Kerr will start in Short's place.
Brady's too experienced to try to trick him. He's seen every coverage and faced every blitz several times over. That places higher importance on the Panthers' defenders winning their individual matchups.
It also means the Panthers have to be better on first and second down, giving them third down rushing opportunities. Defensive coordinator Phil Snow pointed out this week that eight of the Raiders' third downs came with five yards or fewer to go. That allowed Carr to quickly get rid of the ball or hand off to running back Josh Jacobs for a first down. Carolina must get stops on the early downs to bring up more third-and-longs. If that happens, rushers like Brian Burns will get more opportunities to bring Brady down.
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Can the Panthers limit rushing touchdowns?
The Panthers tied a modern-NFL record by allowing 31 rushing touchdowns a season ago, and that trend continued in Week 1. Jacobs scored three rushing touchdowns last week, which doesn't look good when factored out through an entire season.
Tampa Bay has a pair of talented rushers who could be tough to stop near the goal line. Ronald Jones had 66 yards on 17 carries last week. Former first-round pick Leonard Fournette recorded just five yards on five carries but rushed for 1,152 yards a season ago.
Carolina's defensive issues are interconnected. If the team is better on first and second down, that will limit third-and-manageable opportunities. If the Buccaneers convert fewer third downs, they'll have fewer possessions end in the red zone. And if they're not in the red zone, the Panthers will have fewer chances to surrender rushing touchdowns.
How will the Panthers' pass protection hold up?
Carolina kept quarterback Teddy Bridgewater relatively clean last Sunday. He took one sack and sustained three quarterback hits in the loss to Las Vegas, and Bridgewater said he should have thrown the ball before the sack occurred. But the Raiders aren't known for their pass rush. Tampa Bay has last year's sack champion.
Shaquil Barrett racked up 19.5 sacks in 2019. While he didn't have any last week, Bucs head coach Bruce Arians said he was close to getting two on Saints quarterback Drew Brees.
Barrett can wreck a game, plus, the Bucs have veteran lineman Jason Pierre-Paul rushing from the opposite side. Defensive tackles Ndamukong Suh and Vita Vea are strong enough to generate interior pressure as well. If the Panthers can keep themselves out of third-and-long situations, that will reduce the chances for the Buccaneers pass rush to ruin their day.
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Brady vs. the Panthers secondary
Brady had an up-and-down performance against the Saints last week. He completed 64 percent of his passes for 239 yards and two touchdowns. But he also threw a pair of interceptions, one of which was returned for a touchdown.
Brady's now thrown a pick-six in each of his last three games — the Patriots' regular-season finale against the Dolphins, the Wild Card round matchup against the Titans, and last week to New Orleans.
Still, Brady displayed he's still able to make accurate, downfield throws to challenge a secondary. Though Panthers cornerback Donte Jackson left last week's game with an ankle injury, he's expected to play. Carolina plans to rotate Jackson, Rasul Douglas, and rookie Troy Pride Jr. at the position. Based on Arians' offense, Brady will likely test those corners more than the Raiders did last week. If they hold up, the Panthers will have a much better shot to win.
Carolina is 25-19 all-time against the Tampa Bay Buccaneers, posting a 13-10 record at home and 12-9 on the road.
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Carolina Panthers' Jonathan Stewart (28) runs past Tampa Bay Buccaneers' Quincy Black (58) and Ronde Barber (20) during an NFL football game on Sunday, Dec.6, 2009 in Charlotte, N.C. (AP Photo/Rick Havner)
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Carolina Panthers' Stephen Davis (48) scores on a 1-yard touchdown run against the Tampa Bay Buccaneers during the second quarter on Sunday, Nov. 6, 2005, in Tampa, Fla. (AP Photo/Scott Audette)
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Carolina Panthers against the Tampa Bay Buccaneers during a game at Bank of American Stadium on Sunday, December 24, 2017 in Charlotte, NC. (Photo by Melissa Melvin-Rodriguez)
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Carolina Panthers against the Tampa Bay Buccaneers during a game at Bank of American Stadium on Sunday, December 24, 2017 in Charlotte, NC. (Photo by Melissa Melvin-Rodriguez)
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Carolina Panthers against the Tampa Bay Buccaneers during a game at Bank of American Stadium on Sunday, December 24, 2017 in Charlotte, NC. (Photo by Melissa Melvin-Rodriguez)
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Carolina Panthers play against the Tampa Bay Buccaneers on Sunday, December 1, 2013.
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Carolina Panthers play against the Tampa Bay Buccaneers on Sunday, October 4, 2015 in Tampa, FL.
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Carolina Panthers play against the Tampa Bay Buccaneers on Monday, October 10, 2016 at Bank of America Stadium in Charlotte, NC.
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Carolina Panthers play against the Tampa Bay Buccaneers on Sunday, December 1, 2013.
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Carolina Panthers play against the Tampa Bay Bucaneers at Bank of America Stadium on Sunday, December 14, 2014 in Charlotte, NC.
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Carolina Panthers play against the Tampa Bay Bucaneers at Bank of America Stadium on Sunday, December 14, 2014 in Charlotte, NC.
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Tampa Bay Buccaneers' Josh McCown (12) looks for an open receiver as Carolina Panthers' Charles Johnson (95) runs after him during the second half of an NFL football game in Charlotte, N.C., Sunday, Dec. 14, 2014. The Panthers won 19-17. (AP Photo/Bob Leverone)
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Carolina Panthers play against the Tampa Bay Buccaneers on Monday, October 10, 2016 at Bank of America Stadium in Charlotte, NC.
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Carolina Panthers against the Tampa Bay Buccaneers during a game at Bank of American Stadium on Sunday, December 24, 2017 in Charlotte, NC. (Photo by Jamey Price)
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Carolina Panthers against the Tampa Bay Buccaneers during a game at Bank of American Stadium on Sunday, December 24, 2017 in Charlotte, NC. (Photo by Melissa Melvin-Rodriguez)
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Carolina Panthers play against the Tampa Bay Buccaneers on Sunday, December 1, 2013.
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Carolina Panthers play against the Tampa Bay Buccaneers on Monday, October 10, 2016 at Bank of America Stadium in Charlotte, NC.
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Carolina Panthers play against the Tampa Bay Buccaneers on Sunday, December 1, 2013.
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Carolina Panthers play against the Tampa Bay Buccaneers on Sunday, October 4, 2015 in Tampa, FL.
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Carolina Panthers play against the Tampa Bay Buccaneers on Monday, October 10, 2016 at Bank of America Stadium in Charlotte, NC.
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Carolina Panthers against the Tampa Bay Buccaneers during a game at Bank of American Stadium on Sunday, December 24, 2017 in Charlotte, NC. (Photo by Jamey Price)
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Carolina Panthers play against the Tampa Bay Buccaneers on Sunday, October 4, 2015 in Tampa, FL.
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Carolina Panthers play against the Tampa Bay Buccaneers on Sunday, January 1, 2017 at Raymond James Stadium in Tampa, FL.
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Carolina Panthers play against the Tampa Bay Buccaneers on Sunday, December 1, 2013.
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Carolina Panthers' DeAngelo Williams follows blockers to score during the third quarter of an NFL football game against the Tampa Bay Buccaneers on Sunday, Dec. 30, 2007, in Tampa, Fla. (AP Photo/Chris O'Meara)
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Carolina Panthers' Kawann Short (99) celebrates after recovering a fumble against the Tampa Bay Buccaneers in the second half of an NFL football game in Charlotte, N.C., Sunday, Dec. 14, 2014. (AP Photo/Mike McCarn)
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Carolina Panthers play against the Tampa Bay Buccaneers on Sunday, October 4, 2015 in Tampa, FL.
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Carolina Panthers quarterback Cam Newton (1) celebrates a touchdown by running back Jonathan Stewart (28) against the Tampa Bay Buccaneers during the first quarter of an NFL football game Sunday, Oct. 29, 2017, in Tampa, Fla. (AP Photo/Phelan Ebenhack)
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Carolina Panthers play against the Tampa Bay Buccaneers on Sunday, October 4, 2015 in Tampa, FL.
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Carolina Panthers play against the Tampa Bay Buccaneers on Sunday, January 1, 2017 at Raymond James Stadium in Tampa, FL.
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Carolina Panthers play against the Tampa Bay Buccaneers on Sunday, October 4, 2015 in Tampa, FL.
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Carolina Panthers DeAngelo Williams runs with the football during the game against the Tampa Bay Buccaneers at the Raymond James Stadium in Tampa Bay, Fla., Sunday, Sept. 7, 2014. (Mike McGinnis/AP Images for Panini)
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Carolina Panthers play against the Tampa Bay Buccaneers on Sunday, October 4, 2015 in Tampa, FL.
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Carolina Panthers' Steve Smith (89) catches a touchdown pass as Tampa Bay Buccaneers' Jermaine Phillips (23) defends during the third quarter of the Panthers' 38-23 win in an NFL football game in Charlotte, N.C., Monday, Dec. 8, 2008. (AP Photo/Rick Havner)
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Carolina Panthers' Na'il Diggs wraps up Tampa Bay Buccaneers' Mike Alstott during the first half of an NFL game Sunday, Sept. 24, 2006 in Tampa, Fla. The Panthers won 26-24. (AP Photo/Chris O'Meara)
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Carolina Panthers play against the Tampa Bay Bucaneers at Bank of America Stadium on Sunday, December 14, 2014 in Charlotte, NC.
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Carolina Panthers wide receiver Jerricho Cotchery (82) catches a pass in front of Tampa Bay Buccaneers middle linebacker Mason Foster (59) during the second half of an NFL football game in Tampa, Fla., Sunday, Sept. 7, 2014.(AP Photo/Phelan M. Ebenhack)
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Carolina Panthers play against the Tampa Bay Bucaneers at Bank of America Stadium on Sunday, December 14, 2014 in Charlotte, NC.
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Tampa Bay Buccaneers quarterback Chris Simms (2) gets sacked by Carolina Panthers' Julius Peppers during the second quarter Sunday afternoon, Nov. 6, 2005, in Tampa, Fla. (AP Photo/Chris O'Meara)
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Carolina Panthers kicker John Kasay (4) kicks the game-winning field goal with six second remaining in the fourth quarter against the Tampa Bay Buccaneers during a National Football League game Sunday afternoon Sept. 24, 2006 in Tampa, Fla. The Panthers defeated the Buccaneers 26-24. (AP Photo/Chris O'Meara)

Carolina Panthers' Steve Smith, left, grabs a first-quarter touchdown pass from quarterback Rodney Peete in front of Tampa Bay Buccaneers safety John Lynch, Sunday, Nov. 17, 2002, in Tampa, Fla. (AP Photo/Scott Martin)

Carolina Panthers quarterback Derek Anderson (3) throws a pass during the first half of an NFL football game against the Tampa Bay Buccaneers in Tampa, Fla., Sunday, Sept. 7, 2014.(AP Photo/Phelan M. Ebenhack)

Carolina Panthers running back Jonathan Stewart (28) gtes ahead of Tampa Bay Buccaneers defensive back Elbert Mack (33) on a run during the first quarter of an NFL football game Sunday, Dec. 4, 2011, in Tampa, Fla. (AP Photo/Margaret Bowles)

Tampa Bay Buccaneers quarterback Jeff Garcia (7) is sacked by Carolina Panthers' Tyler Brayton (96) during the first quarter of an NFL football game in Charlotte, N.C., Monday, Dec. 8, 2008. (AP Photo/Rick Havner)

Carolina Panthers running back DeShaun Foster runs for yardage during an NFL football game against the Tampa Bay Buccaneers in Charlotte, N.C., Sunday, Sept. 30, 2007. (AP Photo/Chuck Burton)
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
In this Dec. 8, 2008 photo, Carolina Panthers running back Jonathan Stewart (28) and Panthers' DeAngelo Williams celebrate after Stewart's touchdown in the fourth quarter of an NFL football game against the Tampa Bay Buccaneers in Charlotte, N.C. Smash and Dash. The nickname coined for the panthers running backs Jonathan Stewart (Smash) and DeAngelo Williams (Dash) is catching on as defenders bounce off. The Panthers now hope this young tandem lead them into the playoffs. (AP Photo/Chuck Burton)

Carolina Panthers' DeAngelo Williams (34) runs past Tampa Bay Buccaneers' Derrick Brooks (55) for a touchdown in the fourth quarter of an NFL football game in Charlotte, N.C., Monday, Dec. 8, 2008. (AP Photo/Chuck Burton)
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
Tampa Bay Buccaneers running back Michael Pittman (32) attempts to dive over the Carolina Panthers defense, including Will Witherspoon (54) and Brian Allen (52) during the second quarter Sunday, Nov. 17, 2002, in Tampa, Fla. Pittman was stopped short of the end zone. (AP Photo/Chris O'Meara)

Carolina Panthers quarterback Jake Delhomme fires a first-quarter pass while Panthers tackle Travelle Wharton (70) keeps Tampa Bay Buccaneers' Simeon Rice (97) out of the play Sunday, Nov. 6, 2005 in Tampa, Fla. The Panthers defeated the Buccaneers 34-14. (AP Photo/Chris O'Meara)

Carolina Panthers wide receiver Ricky Proehl runs away from Tampa Bay Buccaneers safety Will Allen (26) after pulling in a 64-yard reception from quarterback Jake Delhomme during the second quarter Sunday afternoon, Nov. 6, 2005, in Tampa, Fla. (AP Photo/Chris O'Meara)

Carolina Panthers cornerback Chris Gamble (20) gets pulled down by Tampa Bay Buccaneers' Joey Galloway after intercepting a first quarter pass from Buccaneers quarterback Chris Simms during a National Football League game Sunday afternoon Sept. 24, 2006 in Tampa, Fla. (AP Photo/Chris O'Meara)

Carolina Panthers' Julius Peppers (90) runs an interception 46 yards for a touchdown as Panthers coach John Fox, back left, celebrates in the third quarter of the Panthers' 21-14 win over the Tampa Bay Buccaneers, Sunday, Nov. 28, 2004, in Charlotte, N.C. (AP Photo/Rusty Burroughs)
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
Carolina Panthers' Karl Hankton (88) reaches for the ball after a punt attempt by Tampa Bay Buccaneers' Josh Bidwell (9) was blocked during the first quarter Sunday, Dec. 26, 2004, at Raymond James Stadium in Tampa, Fla. (AP Photo/Steve Nesius)

Carolina Panthers' Mike Rucker (93) celebrates after sacking Tampa Bay Buccaneers quarterback Chris Simms (2) during the second half Sunday, Nov. 6, 2005, in Tampa, Fla. Helping Simms up is Buccaneers center John Wade (76). (AP Photo/Steve Nesius)

Carolina Panthers' Steve Smith (89) reacts after his game-winning five-yard touchdown catch as Tampa Bay Buccaneers players Corey Ivy (35) and Shelton Quarles (53) stand by during the final minutes of the fourth quarter of the Panthers' 27-24 win in Charlotte, N.C., Sunday, Nov. 9, 2003. (AP Photo/Rick Havner)
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
Carolina is 12-9 at home against Tampa Bay all-time. The Buccaneers have won the last two games in Charlotte, including a 43-26 decision last year.
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