The Carolina Panthers (5-9) travel to the Indianapolis Colts (6-8) for the Panthers' last road game of the season.

Matchup Stats

• Carolina has lost six games in a row, while Indianapolis has lost four games in a row.
• The Panthers lead the all-time series with Indianapolis, 5-1, including a 29-26 overtime win in the most recent matchup in 2015.
• Carolina has gone 3-0 against the AFC South this season with Sunday's game marking a chance for a division sweep. It would mark the third time in five years that the Panthers have swept their AFC opponents.
• Indianapolis head coach Frank Reich was the first quarterback signed in Panthers history and threw the first Panthers TD pass in 1995 at Atlanta in Week 1.
• Running back Marlon Mack has 919 rushing yards and five rushing touchdowns for the Colts.
• Quarterback Jacoby Brissett completed 64.8 percent of his passes for 1,649 yards, 14 touchdowns, three interceptions and a 99.7 quarterback rating in the first half of the season. In the second half, he's completing just 58.5 percent of his throws, picking up 1,012 yards, four touchdowns, three interceptions and a 77.9 passer rating.

Individual Stats

• With two games remaining, Christian McCaffrey is in a three-horse race for the NFL's rushing title. Nick Chubb (1,408), Derrick Henry (1,329) and McCaffrey (1,307) all have more than a 100 more rushing yards than fourth-place Chris Carson. No Panther has ever won the league's rushing title.
• McCaffrey leads the NFL in scrimmage yards (2,121), becoming the ninth player with over 2,100 scrimmage yards through Week 15 in the Super Bowl era. He passed Steve Smith's previous franchise record for all-purpose yards (1,994, 2001).
• McCaffrey now has six games with over 175 scrimmage yards this season, tying O.J. Simpson and Jim Brown for the most such games in one season.
• DJ Moore now ranks third in the NFL in receiving yards with 1,174.
• McCaffrey and Moore have combined for 3,335 scrimmage yards, the most by any RB-WR duo in the NFL this year. The NFL record for most yards by a RB-WR duo in one season is 3,716 by Edgerrin James and Marvin Harrison in 2000.
• Panthers defenders Luke Kuechly (131), Eric Reid (112) and Shaq Thompson (109) all have over 100 tackles, marking the first time in franchise history that Carolina has had three 100-tackle players in the same season. The last NFL team to do it was Jacksonville in 2016.

Milestones to Watch

• Carolina (6) needs three touchdowns from 50 or more yards to break the franchise record for most 50+ yard touchdowns (8, 1999).
• The Panthers (49) need 11 sacks to tie the franchise record (60) set in 1996 and 2013.
• Christian McCaffrey (1,307) needs 209 rushing yards to eclipse DeAngelo Williams' franchise record (1,515, 2008) for rushing yards in a season.
• With six receptions, McCaffrey would become the second player in NFL history with 2,000+ scrimmage yards and 100+ receptions, joining LaDainian Tomlinson (2003).
• With six receptions, McCaffrey would top 100 receptions for the second-consecutive season, becoming the first running back in NFL history with two or more 100-catch seasons.
• McCaffrey (814) needs 54 receiving yards to break his own franchise record (867) for most receiving yards by a running back. He needs 186 receiving yards to become the third player in NFL history (Marshall Faulk, Roger Craig) with 1,000 rushing yards and 1,000 receiving yards in one season.
• McCaffrey currently has 14 rushing and four receiving touchdowns this season. With one rushing and one receiving touchdown, he would join Ahman Green (2003), Marshall Faulk (2000) and O.J. Simpson (1975) as the only players with 15+ rushing and 5+ receiving touchdowns in one season.
• If McCaffrey (18) gets two total touchdowns, he will tie DeAngelo Williams (20, 2008) for the most total TDs in one season in franchise history.
• DJ Moore needs 14 receptions for 100 on the season, becoming the fourth player in franchise history with 100 catches. If Moore tallies 14 catches and McCaffrey has six catches, it will mark the first time in NFL history that a team's running back and wide receiver both went over 100 catches.
• Will Grier could become the first Panthers quarterback born in the Carolinas to throw a touchdown in a game.
• Mario Addison (55.0) needs 1.0 sack to pass Mike Rucker (55.5) for third place all-time in franchise history. He would also record his second career double-digit sack season.
• Eric Reid (112) needs five tackles to pass Mike Minter (116, 2000) for the most tackles by a safety in one season in franchise history. He needs one sack to be in sole first place for the most sacks by a safety in one season in franchise history (Toi Cook, 1996, 4.0).